​Here’s a particularly perceptive comment that has stuck in my mind, from a fellow cyclist on a group ride one Sunday morning: “Have you noticed the wind is either against you or you’re feeling really good today?”. If a ride feels easy, it’s never because there is a howling tailwind blowing you along, you’ve just miraculously become super-fit. A deep comment indeed for a blurry-eyed Sunday morning!
 
Of course as scientists we would never do this, would we? We would never see a funded grant as a sign that we wrote a good project but question the judgement of the committee if our next grant application is rejected. And if we arrive late for a meeting, we would never blame the traffic that held us up, rather than the fact that we left it too late starting our journey there. Of course not!
 
Self-serving bias is everywhere, and this includes scientists – all of us! We don’t usually see it, at least not in ourselves, because like everyone we have a ‘bias blindspot’. Only ‘other people’ are irrational, not us!  

Self-serving bias has a close cousin: in-group bias. We may tell ourselves our group does better science than our competitors, that our generation has dealt with more hardship than others, that ‘all’ people in other job types (administrators, journal editors, funders, support staff, etc.) are not as committed as we are, or are less reasonable people.
 
As supposedly rational scientists, shouldn’t we make sure we have all the information we need before we form these beliefs? What makes us think we have sufficient knowledge of those other people’s lives, or indeed that we have an objective view of our own life? But every day we find ourselves slipping into these ways of thinking.
 
We are human after all, and these are common thinking errors that occur over and over in human thinking. But here’s the big question: how much anguish do we create for ourselves, and for our colleagues, by thinking this way?

We know how it goes – a day spent reacting to other people’s emails or “quick chats” while our own to do list remains untouched at the end. Or losing ourselves in the first item on our list so other, often more important tasks don’t get a look in.
 
Yet another day of not living up to our potential but we know it’s there inside us. Sports psychologist and coach Tim Galwey summed this up with the equation:
 

• Performance   =   potential   -   interference

 
Interference, in turn, is made up of external and internal factors. We often prefer to blame the external ones, remaining blind to the many ways we indulge in self-sabotage.  So, what else is going on inside us that holds us back?
 
The heuristics, or thinking short cuts, described in Tversky and Kahneman’s landmark 1974 article play important roles here, especially when we are unaware of how much we use them. The previous article describes how one of them, representativeness, plays out in a scientific workplace and this one covers the other two: availability and anchoring. Could greater awareness of these make our research lives a little more efficient and less hard to handle?

Nobel Prize winner Daniel Kahneman and his colleague Amos Tversky changed how psychologists, economists and politicians think about how we think. In 1974, they published a landmark article on flaws in human decision making, titled ‘Judgement under uncertainty: heuristics and biases’. Using familiar examples from everyday life, they communicated what psychologists had recognised for decades and quantified it with some simple but ingenious experiments. Their work helped spark the rise of the self-help industry and, along with their later work on loss aversion, led to the Nobel Prize for economics for Kahneman (after Tversky’s death). He also disseminated these findings in many easily accessible forms, such as his books ‘Thinking, fast and slow’ and ‘Noise’ and many podcast interviews.   

​Crucially, they warned, “Experienced researchers are also prone to the same biases”. Indeed, Kahneman describes how they developed their hypotheses by looking at, and laughing at, the flaws in their own thinking, an inspirational example of how humility strengthens research.
 
So, half a Century on, what can we learn from Kahneman and Tversky about the flaws in our own thinking? By becoming more aware of them, can we strengthen not only our research but also our wellbeing as we carry out that research? Can we use more critical thinking about our own thinking? 

​When did you last compare yourself with someone else? Five minutes ago? Ten? Be honest! If you think you’ve not done it today, did you just wake up or did you not notice?
 
Now think about how you design a good experiment. If you work with patients, you would never compare questionnaire-based data from one group with biomarker measurements of another, would you? Or in cell culture experiments, would you compare micrographs from the test condition with western blots from controls? Of course not! No scientist would ever base conclusions on two unmatched datasets, would we?
 
Except when we do! When we compare our own presentation with the next speaker’s, this is exactly what we do, comparing our feelings with their outward appearance. We cannot see how we appear to others and we know next to nothing about their feelings.
 
We also do it when we compare our worth as a scientist with the person who just landed the job we applied for. We consider our latest rejection along with the battle scars of all our previous ones, while knowing nothing about their rejected applications which could even outnumber ours. Negativity bias adds yet more fuel to the fire. So much for matched datasets and logical thinking!

​We often do equally illogical things when something goes wrong. When an experiment fails, for example, we can quickly find ourselves asking which reagent is off, whether the equipment is faulty, or even looking for ways to pin blame on someone else, perhaps even on the weather. Then later we find out we’d misread the protocol. When a reviewer criticises our paper, we imagine we know their personality and intentions despite having no idea who it is and no facial expressions to guide us. Why do we delude ourselves like this?
 
This is our everyday life as researchers, getting ourselves into all kinds of misunderstandings and confusion: black-and-white thinking, confusing opinion with fact, misattributing causality, confirmation bias, undue negativity and more. We see it in others all the time but we are blind to it in ourselves.
 
Why do we do this to ourselves? How much easier would our life be with more clarity in our thinking? And can we at least move a little in that direction?

​When I did my PhD, I remember how excited I felt when I found a book called ‘How to get a PhD’. I have long since lost my copy and forgotten almost everything in it. Apart from one thing: the section on isolation.
 
I’d never thought of it this way before, but this section resonated with me immediately. Family and friends didn’t seem to understand my research or the lifestyle around it. Meanwhile, talking to colleagues about my doubts or fears seemed off limits.  Everyone else appeared to have it all ‘under control’ and no-one discussed such things. As the failed experiments piled up, and my thoughts of what I could achieve got scaled down, this felt increasingly uncomfortable. Finally, here was a book that talked my language!

​A lot of time has passed. Today, we have social media, other excellent books and courses, graduate programmes, and mentoring initiatives. But isolation remains an issue.
 
I’ve often felt isolated as a PI too. This seems paradoxical because a PI’s job involves far more people interaction than working at the bench does. But feeling understood can be further away than ever.
 
Staring at a grant rejection email, knowing I have to break the bad news to my group, is a very lonely place to be.  Figuring out how to handle a challenging workplace conversation, when confidentiality prevents me discussing it with colleagues feels like there is nowhere to turn.
 
In the context of a world with a crisis of isolation outside science too, how can we handle this better? And what can we do to support others?

​What would you miss most if you quit research right now?
 
An answer I often hear is ‘having autonomy’. Academic freedom comes at a price, both financially and metaphorically. But having this level of agency is a huge privilege. If we take that for granted, we allow a culture of negativity to prevail without this vital positive to balance it.

The importance of agency
The feeling of being able to exert control over our environment, and to some extent over our destiny, is one of the most basic human needs. Our brains are wired to feel pleasure from having agency over our lives. Even our health depends on it.
 
At its best, research fulfils this need very well. Many of us have substantial autonomy over our research topic and over how we organise our day, while actually getting paid for it.
 
However, it comes as part of a package in which we seem to have very little agency in other areas of our work. Whether it’s a compulsory training course or a meeting where we feel unable to speak, the contrast could not be greater.

​For people drawn to academic freedom, having less freedom on other issues can seem particularly problematic. It helps to understand why these limits are there, and to ask: ‘What agency do we have?’ and ‘How can we use it?’.    

We all feel out of our depth sometimes. It is normal to experience imposter feelings in these moments, but by managing these feelings better, could we reduce the risk of slipping into the far more damaging  ‘imposter syndrome’?
 
Imposter syndrome shows up in diverse and often damaging ways, including many we don't normally think of this way. These include unhealthy levels of procrastination, overworking, perfectionism and unconscious avoidance, not just a lack of confidence. Which of us doesn’t experience at least one of these sometimes? Imposter feelings, in contrast, could be seen as a ‘growth moment’, a healthy driver of personal development that helps us perform at our best.

​Staying on the right side of this fine line is a challenge. If we had a better understanding of what drives imposter feelings in research, could we learn how to harness their stimulus for growth instead of damaging our wellbeing and productivity?

​There was a political earthquake in the US last week. There are major ongoing wars, climate change, economic uncertainty, a post-pandemic world we are still adapting to, and the new challenge of ‘artificial intelligence’.
 
And somehow, in the middle of all this, we need to stay calm and rational enough to do good science!
 
How does that work?

​You may be relieved to hear this post is not about politics! Or the perceived moral high ground of either 'side'. You may find it helpful to read regardless of where you stand on those issues. It is about finding the clarity and motivation for science in an uncertain world. What are the prospects for science in a world that questions its role in society? And how can we reinforce our own personal values in a changed landscape?

​No-one said it would be easy! We are, after all, pushing back the frontiers. That may sound grand, but there are reasons why the frontiers are where they are.
 
Progress is never as quick as we would all like it to be. The world is imperfect. Equipment breaks, experiments fail, projects run into dead ends, good papers and grant applications get rejected, administration takes time (often far too much), some people let us down, and the world is full of distractions. All of these take time not only from our research but from that of all other scientists. And they have done so, to greater or lesser extents, for generations.

​​Even worse, these problems drain our motivation. We need an unbreakable sense of purpose, and commitment to it, that we can tap into to ride them out. So what is purpose and how do we find it?